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Masafumi Fukagawa Selected Research

Calcium-Sensing Receptors

1/2020Development of evocalcet for unmet needs among calcimimetic agents.
1/2018Pharmacokinetics of evocalcet in secondary hyperparathyroidism patients receiving hemodialysis: first-in-patient clinical trial in Japan.
7/2017A Single- and Multiple-Dose, Multicenter Study of Etelcalcetide in Japanese Hemodialysis Patients With Secondary Hyperparathyroidism.
4/2017Etelcalcetide for the treatment of secondary hyperparathyroidism.
1/2017A 12-week dose-escalating study of etelcalcetide (ONO-5163/AMG 416), a novel intravenous calcimimetic, for secondary hyperparathyroidism in Japanese hemodialysis patients
.
1/2008[Basic and clinical aspects of calcimimetics. Calcimimetics : a promising treatment for persistent hypercalcemia after kidney transplantation].
9/2004[Role of vitamin D in the pathogenesis of renal osteodystrophy].
6/2003Adenovirus-mediated functional gene transfer into parathyroid cells in vivo and in vitro.

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Masafumi Fukagawa Research Topics

Disease

131Secondary Hyperparathyroidism
04/2024 - 01/2002
80Chronic Renal Insufficiency
11/2023 - 02/2005
40Hyperphosphatemia
03/2024 - 02/2005
30Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets)
07/2020 - 09/2004
28Vascular Calcification
03/2024 - 07/2005
23Hyperparathyroidism
11/2023 - 09/2003
23Chronic Kidney Failure (Chronic Renal Failure)
12/2021 - 01/2002
18Kidney Diseases (Kidney Disease)
02/2023 - 05/2007
18Hyperplasia
01/2021 - 12/2002
16Type 2 Diabetes Mellitus (MODY)
10/2021 - 02/2008
15Renal Insufficiency (Renal Failure)
10/2023 - 08/2004
15Bone Diseases (Bone Disease)
05/2019 - 03/2002
14Uremia
01/2021 - 03/2002
14Hypercalcemia (Milk Alkali Syndrome)
10/2019 - 09/2002
13Cardiovascular Diseases (Cardiovascular Disease)
02/2024 - 02/2009
13Inflammation (Inflammations)
05/2021 - 01/2008
12Diabetic Nephropathies (Diabetic Nephropathy)
10/2023 - 09/2004
10Hypocalcemia
04/2024 - 06/2002
9Diabetes Mellitus
04/2024 - 07/2009
9Hypophosphatemia
04/2024 - 07/2005
9Anemia
11/2023 - 05/2009
9Acute Kidney Injury (Acute Renal Failure)
10/2023 - 07/2007
9Body Weight (Weight, Body)
12/2021 - 01/2002
9Fibrosis (Cirrhosis)
12/2021 - 07/2009
8Osteoporosis
03/2024 - 08/2003
8Drug-Related Side Effects and Adverse Reactions
01/2022 - 03/2014
6Primary Hyperparathyroidism
10/2019 - 07/2002
6Metabolic Bone Diseases (Osteopenia)
05/2015 - 09/2002
5Proteinuria
02/2024 - 12/2008
5Diarrhea
11/2023 - 05/2014
5Hyperkalemia
03/2023 - 07/2007
5Adenoma (Adenomas)
01/2019 - 07/2002
5Neoplasms (Cancer)
09/2017 - 09/2011
5Vitamin D Deficiency
01/2016 - 12/2002
5Bone Resorption
06/2011 - 09/2002
4Heart Failure
11/2023 - 12/2018
4Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
06/2022 - 11/2011
4Atherosclerosis
04/2021 - 01/2008
4Hypoparathyroidism
08/2017 - 09/2005
3Atrial Fibrillation
10/2023 - 01/2011
3Albuminuria
10/2023 - 04/2014

Drug/Important Bio-Agent (IBA)

73Parathyroid Hormone (Parathormone)IBA
11/2023 - 03/2002
57MineralsIBA
02/2023 - 01/2002
45Phosphates (Orthophosphate)IBA
03/2024 - 09/2002
42CalciumIBA
03/2024 - 09/2002
35Cinacalcet (Sensipar)FDA Link
04/2024 - 05/2004
34Vitamin DFDA LinkGeneric
03/2024 - 01/2002
28Phosphorus (Red Phosphorus)IBA
11/2023 - 12/2002
23Fibroblast Growth Factor-23IBA
01/2022 - 08/2004
21Calcitriol Receptors (Calcitriol Receptor)IBA
06/2023 - 09/2004
16evocalcetIBA
03/2024 - 01/2018
15IronIBA
11/2023 - 06/2008
11Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2007
11Uremic ToxinsIBA
04/2021 - 04/2011
111,25-dihydroxyvitamin DIBA
07/2020 - 01/2002
10CreatinineIBA
10/2023 - 06/2008
10Calcitriol (Calcijex)FDA LinkGeneric
06/2015 - 06/2003
9etelcalcetide hydrochlorideIBA
03/2024 - 01/2017
9Insulin (Novolin)FDA Link
09/2020 - 02/2008
9maxacalcitolIBA
12/2015 - 09/2003
8tenapanorIBA
11/2023 - 01/2021
8IndicanIBA
12/2021 - 08/2010
8Calcium-Sensing ReceptorsIBA
01/2020 - 06/2003
7Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2008
7ferric citrateIBA
01/2019 - 01/2014
6Hemoglobins (Hemoglobin)IBA
02/2024 - 05/2009
6AlbuminsIBA
10/2023 - 04/2011
6Streptozocin (Streptozotocin)FDA Link
12/2021 - 01/2007
6Sevelamer (RenaGel)FDA Link
01/2018 - 08/2007
6Ethanol (Ethyl Alcohol)IBA
08/2008 - 06/2003
5upacicalcetIBA
03/2024 - 01/2022
5Dialysis SolutionsIBA
02/2024 - 09/2002
5ErythropoietinFDA Link
11/2023 - 06/2008
5lanthanum carbonate (Fosrenol)FDA Link
12/2022 - 11/2005
5AST 120IBA
12/2021 - 07/2009
5Therapeutic UsesIBA
01/2021 - 01/2002
4Calcium Carbonate (Limestone)FDA Link
12/2022 - 11/2005
4NADPH Oxidases (NAD(P)H oxidase)IBA
12/2021 - 04/2013
4Glucose (Dextrose)FDA LinkGeneric
10/2021 - 05/2008
4ThioredoxinsIBA
05/2021 - 01/2007
4Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2020 - 07/2005
4Sulfates (Sulfates, Inorganic)IBA
01/2020 - 04/2013
4Blood Glucose (Blood Sugar)IBA
01/2019 - 01/2013
4Adrenocorticotropic Hormone (ACTH)FDA Link
01/2019 - 12/2014
4Hormones (Hormone)IBA
12/2015 - 02/2009
4Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
01/2014 - 01/2009
4AntioxidantsIBA
04/2011 - 06/2007
3SodiumIBA
03/2024 - 01/2019
3Alkaline PhosphataseIBA
03/2024 - 08/2010
3Ferritins (Ferritin)IBA
11/2023 - 01/2011
3PotassiumIBA
03/2023 - 12/2015
3Uric Acid (Urate)IBA
01/2023 - 01/2017

Therapy/Procedure

107Renal Dialysis (Hemodialysis)
04/2024 - 12/2004
57Therapeutics
11/2023 - 06/2003
21Parathyroidectomy
01/2022 - 07/2002
12Kidney Transplantation
12/2021 - 01/2008
8Peritoneal Dialysis
11/2023 - 12/2011
4Cell- and Tissue-Based Therapy (Cell Therapy)
01/2020 - 09/2011
4Aftercare (After-Treatment)
01/2017 - 08/2010
3Transplantation
01/2023 - 08/2011